This consultancy pursued a double objective. On the one hand, it aimed to identify the main international trends of public initiatives in the promotion of digital transformation and the development of Industry 4.0. This, with the purpose of recovering international “good practices” from which some recommendations to the countries of the Ibero-American space emerge. On the other hand, it was sought to investigate the policies to promote the digital transformation of Ibero-American SMEs, paying special attention to their implementation characteristics. To this end, policies and instruments that promote the digital transformation of SMEs in the following countries were surveyed and analyzed: Spain, Portugal, Argentina, Brazil, Chile, Colombia and Mexico. The study focused on the most recent plans, strategies and instruments around this issue, without neglecting their history and development. The descriptive documentary-type approach was guided by previously constructed categories given the methodological strategy used In this way, the characteristics of design and execution of the policies to promote the digital transformation of SMEs were analyzed, with special emphasis on coordination between the different levels of public bodies and ministries, public-private dialogue bodies, affected budgets and articulated systems for their evaluation and monitoring.